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Fig. 1
Differential effect of ionizing radiation on phenotypes of zebrafish embryos according to irradiated time‐points during early developmental stages. Zebrafish embryos at 24 hpf after irradiation at 2, 4, or 6 hpf with doses of 0, 1, 5, and 10 Gy of radiation. Non‐irradiated control embryos were shown in the left end panels (0 Gy). Whole embryos irradiated at 2 hpf (64‐cell stage) showed the most severe phenotype. At a dose of 10 Gy, embryos irradiated at 2 hpf were dead, whereas those at 4 hpf (blastula stage) or 6 hpf (gastrula stage) showed normal body shape.
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Reprinted from Cell biology international, 43(5), Honjo, Y., Ichinohe, T., Cellular responses to ionizing radiation change quickly over time during early development in zebrafish, 516-527, Copyright (2019) with permission from Elsevier. Full text @ Cell Biol. Int.