ZFIN Image: Nittoli et al., 2019, Fig. 8

Image

Figure Caption

Fig. 8

Regulation of uncx gene expression in relation to Fgf, Nodal and Notch/Delta signaling pathways. Whole-mount in situ hybridization of (A, E, H, I) uncx4.1 and (B–D, E, G, J) uncx at (A) 34 hpf, (B–D) 19 h post fertilization (hpf), (E, F, H) 24 hpf, (G) 18 hpf, and (J) 19 hpf. Lateral view, anterior to left. Expression of (A) uncx4.1 and (B) uncx in acerebellar (ace) mutant embryo at (A) 34 hpf and (B) 19 hpf. (C, D) Expression of uncx in embryos treated with (C) DMSO and (D) SU5402 at 19 hpf. (E, F) Expression of (E) uncx4.1 and (F) uncx in cyclops (cyc) mutant embryo at 24 hpf (controls in Fig. 3F and 5H, respectively). (G) Expression of uncx in embryo treated with SB431542 at 18 hpf (control in Fig. 5B). (H–J) Expression of (H, I) uncx4.1 and (J) uncx in embryos treated with (H) DMSO and (I, J) DAPT at (H, I) 24 hpf and (J) 19 hpf. (J) Control in (C).

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Gene X