ZFIN Image: Stankiewicz et al., 2019, Fig. 4

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Figure Caption

Fig. 4

Chronic HCI alters proliferative capacity of zebrafish brain. Representative cerebellar images and corresponding schematics in 1-year-old Control (left column, top) and HCI (right column, bottom) zebrafish on day 3 of BrdU-EdU pulse-chase. A, B, Rostral valvula cerebelli (corresponding to Wulliman et al., 1996, atlas section 179). C, D, Valvula cerebelli (corresponding to Wulliman et al., 1996, atlas section 196). E, F, Caudal valvula cerebelli and rostral corpus cerebelli (corresponding to Wulliman et al., 1996, atlas sections 201–204). G, H, End of valvula cerebelli and mid corpus cerebelli (corresponding to Wulliman et al., 1996, atlas sections 213–219). TeO, Optic tectum; Ctec, commissura tecti; TeV, tectal ventricle; PML, posterior mesencephalic layer; RV, rhombencephalic ventricle; TL, torus longitudinalis. Dashed line indicates neurogenic cerebellar niche regions. Red represents BrdU-only. Green represents EdU-only. Yellow represents BrdU/EdU colocalized. Scale bar, 50 μm.

Acknowledgments

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