Fig. 7
T4 treatment alleviates phenotypic anomalies in duox mutants. T4-treated mutants show an improvement in fin health, compared to untreated mutants (A,B). Pigment changes are evident among T4-treated mutants. C–F show a 5× magnification of the distribution of melanophores on the flank region of sa9892+/− and sa989−/− siblings, with a significant reduction in melanophore number (G). Asterisks denote statistically significant differences (Bonferroni's multiple comparisons test, ****P<0.0001). Goitres resolve following T4 administration, but small ectopic thyroids are still evident (black arrowheads) (I,J). Scale bars: 1 mm.