ZFIN Image: Wang et al., 2018, Fig. 4

Image

Figure Caption

Fig. 4

Triptolide suppressed podocyte apoptosis. (A) 84 hpf larvae treated with MTZ for 24?h exhibit remarkable podocyte apoptosis signalling compared to the untreated group (CTL) on immunostains against cleaved caspase-3. The number of apoptotic cells was significantly reduced in the triptolide treatment group. (B) Quantification of caspase-3-stained area (green) to mCherry (red). Data are expressed as the means?�?SEM. The confocal images are shown at a maximum intensity projection. (n?=?3), **P?<?0.01; *P?<?0.05. (Original magnification, x1000). (C) Annexin V-FITC/PI staining followed by FCM showed podocytes apoptosis induced by PAN was alleviated by triptolide. **P?<?0.01. (On the basis of three triplicate tests).

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.