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Fig. S2
zebrafish hhex mutants exhibit facial lymphatic defects at 5 dpf
(a-b) Facial lymphatic network of 5 dpf Tg(-5.2lyve1b:DsRed); hhex+/+ and hhex-/- larvae; hhex-/- exhibit defects in facial lymphatic vessel formation (arrowheads indicate facial lymphatics, asterisks indicate lack of these structures in hhex mutant). (c-e) Percentage formation of lateral facial lymphatic (LFL) (c), otolithic lymphatic (OLV) (d) and branchial arch lymphatic (LAA) (e) in hhex+/? (n=5) and hhex-/- (n=5). Values represent means ± s.e.m. ****P ≤ 0.0001, **P ≤0.01 and *P ≤ 0.05 by t-test. Scale bars: 100 μm.
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Full text @ Nat. Commun.