Image
|
Figure Caption
Fig. 2
Thoracic duct is absent in etv2 mutant larvae. Confocal microscopy analysis of the thoracic duct (arrows) in wild-type siblings and etv2 mutant larvae in fli1a:GFP; prox1a:RFP background at 4 dpf. Note the absence of the thoracic duct (asterisks) and abnormal vascular patterning in etv2 mutants. (A′,B′) Higher magnification images of larvae in A,B. DA, dorsal aorta, PCV, posterior cardinal vein.
Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Biology, 440(1), Davis, J.A., Koenig, A.L., Lubert, A., Chestnut, B., Liu, F., Desai, S.P., Winkler, T., Pociute, K., Choi, K., Sumanas, S., ETS transcription factor Etsrp / Etv2 is required for lymphangiogenesis and directly regulates vegfr3 / flt4 expression, 40-52, Copyright (2018) with permission from Elsevier. Full text @ Dev. Biol.