Image
|
Figure Caption
Fig. 5
The role of Hars in regulating vascular development is functionally conserved between zebrafish and humans. (A) Hars protein sequence alignment shows high homology between the three species tested. (B,C) Injection of human HARS mRNA rescues ectopic brain vascular branching in zebrafish hars−/−, indicating a conserved regulatory function of Hars in vascular development between zebrafish and humans. (D) Confocal immunofluorescence microscopy shows nuclear localization of endogenous HARS in HUVECs. Scale bars, 50 μm.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ FEBS Open Bio