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Fig. S5
mir-126 MO injections cause lymphatic defects. (A) mir-126 MO injection inhibits TD formation; top, uninjected sibling; bottom, larva injected with 16 ng of mir-126 MO (brightfield and confocal images; 5 dpf animals shown). The TD is mostly missing in mir-126 morphants. (B) Representative quantification of TD formation (as percentage of segments with formed TD) and vISVs (venous sprouting). At least 16 injected larvae analysed per experiment; 4 independent experiments.
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Reprinted from Developmental Biology, 437(2), Kontarakis, Z., Rossi, A., Ramas, S., Dellinger, M.T., Stainier, D.Y.R., Mir-126 is a conserved modulator of lymphatic development, 120-130, Copyright (2018) with permission from Elsevier. Full text @ Dev. Biol.