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Fig. S6
Effects of BMS-833923 on scale regeneration. BMS-833923 was injected in M848:GFP fish 1 day after scale removal, and the fish were stained with Alizarin red at 4 days. Three consecutive scales were removed. The regenerated scales are reduced in size (by 44.0%; see quantification in Fig. 7C), accompanied by a reduction in marginal cells (Fig. 7D). GFP is strongly expressed in the regenerated scale due to an increase in the number of central cells. Scale bar, 500 µm.
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Reprinted from Developmental Biology, 437(2), Iwasaki, M., Kuroda, J., Kawakami, K., Wada, H., Epidermal regulation of bone morphogenesis through the development and regeneration of osteoblasts in the zebrafish scale, 105-119, Copyright (2018) with permission from Elsevier. Full text @ Dev. Biol.