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Fig. S5
Reduced RA signaling does not impair closure of the superior ocular sulcus.
(A) Lateral view of a 28 hpf zebrafish eye following in situ hybridization for cyp1b1. Note that expression extends into the dorsal eye. (B) Quantification of open SOS in 28 hpf embryos from cyp1b1+/- incrosses treated from 10 hpf with control solution or the Aldh inhibitor DEAB. N = 3 experiments, n = number of embryos. Data are means ± SEM. Statistics is two-way ANOVA with Tukey's test. Scale bar is 50 μm. ns, not significant.
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