ZFIN Image: Wopat et al., 2018, Fig. 1

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Figure Caption

Fig. 1

The Notochord Sheath Displays a Segmented Pattern Prior to Vertebral Body Formation

(A) Live confocal imaging of notochord segmentation (denoted by brackets) and osteoblast recruitment (arrows) in col9a2:GFPCaaX and osx:mcherry-NTR fish.

(B) Live confocal imaging showing that osteoblasts specifically migrate to col9a2-negative domains (brackets) in an anteroposterior manner.

(C) Live imaging of calcein stained col9a2:mcherry fish showing that col9a2-negative domains (denoted by asterisks) become mineralized.

Developmental stages are based on standard length. All scale bars are 100 μm. Images in (A) and (C) are digitally stitched.

Acknowledgments

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