ZFIN Image: Auer et al., 2018, Fig. 3

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Figure Caption

Fig. 3

Long-Term Extension of Myelin Sheaths Compensates for Body Growth

(A) Photographs of zebrafish at 4 and at 28 days post-fertilization (dpf). Scale bar, 1 mm.

(B) Quantification of the relative increase of sheath length from their respective initiation onward compared to the increase in somite length over the same time. Data are expressed as mean ± SD.

(B′) Quantification shown in (B) corrected for increase in body growth. Data are expressed as median with interquartile range (Wilcoxon signed-rank test).

(C) Correlation between measured sheath length and their predicted length using increase in somite size as a reference.

(D–D′′′) Timeline of confocal images of an individual cntn1b:mCherry, cntn1b:NFacsa-EYFP co-expressing neuron in the zebrafish spinal cord between 5 and 14 dpf. Scale bar, 100 μm (D and D′).

(D″) Quantification of sheath lengths along the axon shown in (D) between 5 and 14 dpf.

(D′′′) Quantification shown in (D″) corrected for animal body growth.