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Fig. 8
Global misexpression ofsox2orsox3. (A-F) Expression of pax2a (A-C) and pax8 (D-F) at 12 hpf in control embryos (A, D), hs:sox2/+ heterozygotes (B, E) and hs:sox3/+ heterozygotes (C, F) that were heat shocked at 9 hpf, 39 °C for 60 min. (G-L) Expression of pax2a (G-I) and pax8 (J-L) at 14 hpf in control embryos (G, J), hs:sox2/+ heterozygotes (H, K) and hs:sox2/hs:sox2 homozygotes (I, L) that were heat shocked at 12 hpf, 39 °C for 60 min. Embryonic staging was confirmed with myoD expression in somites. All images show dorsal views with anterior to the top.
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Reprinted from Developmental Biology, 435(1), Gou, Y., Guo, J., Maulding, K., Riley, B.B., sox2 and sox3 cooperate to regulate otic/epibranchial placode induction in zebrafish, 84-95, Copyright (2018) with permission from Elsevier. Full text @ Dev. Biol.