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Fig. 4

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ZDB-IMAGE-180511-39
Antibodies
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Figures for Berger et al., 2018
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Figure Caption

Fig. 4

All cct Mutants Show Retina Degeneration, Except for cct5tf212b

(A) H&E-stained sections of 3-dpf-old cct3sa1761 mutants showed severe retina degeneration (n = 11 per genotype) accompanied by abundant apoptosis detected by TUNEL assay (n = 6 per genotype).

(B) At 3 dpf, retina degeneration was also apparent on H&E-stained sections of the insertion mutant cct5hi2972Tg but not of the missense mutant cct5tf212b (n = 11 per genotype).

(C) Pursuant to the retina degeneration, immunohistochemistry with antibodies against acetylated α-tubulin detected neurite defects in the tectum (arrowheads) of cct3sa1761 and cct5hi2972Tg but not cct5tf212b homozygotes (n = 4 per genotype).

See also Figure S6.

Figure Data
Acknowledgments
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