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Fig. 2
Histology of 8-month-old gr −/− and gr +/+ zebrafish. All histological images of 8-month-old gr −/− and gr +/+ zebrafish were taken from longitudinal sections stained with haematoxylin and eosin (H&E). The left panels represent wild type fish, whereas the middle and right panels show tissues from two mutant fish. (A) heart; (B) particular of the heart at higher magnification showing reduced trabecular network in the mutant samples; (C) intestinal mucosa with sloughing epithelium at the villous tips and reduced height of villi in mutants; (D) visceral view showing reduced extension of pancreas in mutants; (E) consistent increase of subcutaneous adipose tissue in mutants. ba = bulbus arteriosus; v = ventricle; a = adipose tissue; i = intestine; p = pancreas; t = trabeculae.