ZFIN Image: Kuo et al., 2016, Fig. S5

Image

Figure Caption

Fig. S5

Morpholino (MO) knockdown of pycr in zebrafish affects somatogenesis and cerebral hemorrhage during embryonic stages. (A) Each pycr MO (7.5 ng) was injected into wild-type zebrafish embryos at the 1- to 2-cell stage and evaluated at 48 hours post fertilization (hpf). The major defects of pycr1-morphants (left panel) or pycr3-morphants (right panel) were reduced body length and a curly tail. The pycr2-MO injected embryos exhibited no obvious abnormality, but the morphants shows cerebral hemorrhage (middle panel). Arrows indicate area of hemorrhage. Lateral views of representative wild-type control (Ctrl) or MO-injected fish were photographed at 48 hpf. Bar: 100 µm. (B) Phenotypic distributions of pycr1, pycr2 and pycr3 morphants.

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Phenotype details

Acknowledgments

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