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Fig. S4
Endodermal expression of Gα13 rescues endocardial-cell migration in the context of global Gα13 deficiency. Epifluorescence images of anterior region of 26-hpf Tg(fli:EGFP) (A-B) and Tg(fli:EGFP/sox17:mCherry-2A-gna13a) (C-D) embryos. The endoderm is marked by mCherry 2 (magenta in C, D) and endothelial cells are marked by EGFP (green; white arrowheads). Dorsoanterior view with anterior up. Scale bar: 100 μm.
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Reprinted from Developmental Biology, 414, Xie, H., Ye, D., Sepich, D., Lin, F., S1pr2/Gα13 signaling regulates the migration of endocardial precursors by controlling endoderm convergence, 228-43, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.