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Fig. 7
Embryonic careg-positive CMs contribute to the trabecular myocardium.
(a) Schematic representation of the transgenic strains used for lineage tracing. (b) Experimental design. (c,d) Longitudinal sections of hearts at 21 d.p.f. immunostained against mCherry (red), GFP (green) and Tropomyosin (blue). (c) Control embryos treated with the vehicle do not display mCherry fluorescence. (d) mCherry+ CMs are present in the trabecular and outer myocardium at 21 d.p.f. in embryos treated with 4-OHT, suggesting that the trabecular myocardium derives from embryonic careg+ CMs. N=9.
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Full text @ Nat. Commun.