Fig. 2
Naïve adult rag1−/− zebra fish are more resistant to lethal spring viremia carp virus (SVCV) infection than rag1+/+ zebra fish. (A) Kaplan–Meier survival curves of naïve rag1−/− (n = 84) and rag+/+ (n = 100) adult zebra fish after exposure to a lethal dose of 104 pfu/ml of SVCV under the same challenge conditions as in panel (A). *Statistically significant differences between survival curves between rag1−/− and rag+/+ as determined by the Gehan–Breslow–Wilcoxon test with p < 0.05 (n = 2). Solid lines, rag1−/− zebra fish larvae. Dashed lines, rag+/+ zebra fish larvae. (B) SVCV titers from pooled whole zebra fish (n = 4 zebra fish per genotype) 3 days after SVCV infection as determined by plaque forming unit (pfu) assays.