ZFIN Image: Jacob et al., 2017, Fig. S1

Image

Figure Caption

Fig. S1

Cardiac Left-Right Patterning and Sarcomere Assembly are Unaffected in Paxillin MZ Double Mutants. (A) Whole-mount mRNA in situ hybridization for heart-specific cmlc2 expression at the heart-jogging stage (30 hpf) revealed that asymmetric heart patterning is normal in Paxillin MZ double mutant embryos (indicated by direction of arrows). The number of embryos with proper heart-jogging direction over total number examined is indicated for each genotype. (B) Immunostaining for α-Actinin revealed that sarcomere formation is also normal in Paxillin MZ double mutant embryos. The number of embryos with normal Z-disc organization over total number examined is indicated for each genotype.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 425(1), Jacob, A.E., Amack, J.D., Turner, C.E., Paxillin Genes and Actomyosin Contractility Regulate Myotome Morphogenesis in Zebrafish, 70-84, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.