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Fig. 7
FGF-induced dkk1b expression is dependent on chd. Expression of dkk1b in (A) wild-type embryos, (B) uninjected ichabod embryos, (C) FGF8 mRNA-injected ichabod embryos, and (D) FGF8 mRNA and MOchd-injected ichabod embryos. Expression of chd in (E) wild-type embryos, (F) uninjected ichabod embryos, (G) FGF8 mRNA-injected ichabod embryos, and (H) FGF8 mRNA and MOdkk1b-injected ichabod embryos. All embryos are shown at the shield stage in animal pole views. Scale bars represent 100 µm.
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Reprinted from Developmental Biology, 424(2), Tanaka, S., Hosokawa, H., Weinberg, E.S., Maegawa, S., Chordin and dickkopf-1b are essential for the formation of head structures through activation of the FGF signaling pathway in zebrafish, 189-197, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.