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Fig. S2
Reduction of miR-363
(A) The morpholino targeting miR-363 (MO363 - green) was designed to bind the mature sequence of miR-363. (B) The Expression of miR-363 was reduced by 99 % by MO363-deficiency in zebrafish at 48 hpf (± sd; n=45 animals from 3 independent experiments; p<0,005). (C) miR-363 deficiency resulted in impaired eye development with reduced eye size up to complete loss of eyes. (D,E) Loss of miR-363 did not alter heart rate or contractility (± sd; n≥11).
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