ZFIN Image: Monroe et al., 2016, Fig. 6

Image

Figure Caption

Fig. 6

Hair bundle density in the lagena. (A) Lagena schematic showing the three sampling locations, with an example of location 2 shown in the confocal image. All boxes are 50 × 50 μm and are drawn to scale. (B) For *AB and transgenic lines created on the *AB background, bundle density is significantly different between genotypes and sampling regions (2-way ANOVA, F_5,160 = 8.91, p < 0.001; and F_2,160 = 43.02, p < 0.001, respectively). In sampling region 3, bundle density is significantly higher in Bcl2 fish than in *AB fish (Bonferroni-corrected posthoc, ***p < 0.001). (C) There is a significant difference in lagenar bundle density between wildtype lines (2-way ANOVA, F_2,68 = 9.08, p < 0.001 for genotype main effect), with WIK fish having higher density in region 3 than AB fish (*p < 0.05). (D) There is no difference in bundle density between ET4 and TL fish (2-way ANOVA, F_1,24 = 0.40, p = 0.53 for genotype main effect). Data are presented as mean ± S.E. N = 8–17 fish per genotype.

Figure Data

Phenotype details

Acknowledgments

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Reprinted from Hearing Research, 341, Monroe, J.D., Manning, D.P., Uribe, P.M., Bhandiwad, A., Sisneros, J.A., Smith, M.E., Coffin, A.B., Hearing sensitivity differs between zebrafish lines used in auditory research, 220-231, Copyright (2016) with permission from Elsevier. Full text @ Hear. Res.