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Fig. 7
Altered lammelipodial polarity of the lateral mesoderm after blocking cadherin mechanotransduction. (A) Representative image sequence of a functional lamellipodial protrusion (red arrows) coupled to cell body displacement. The red asterisk marks the cell making protrusions, with the dashed lines indicating the displacement of the cell body. Dorsal to the right. (B) Percentage of lamellipodia coupled to cell body displacement in the direction of the protrusion by at least half the diameter of the cell. The number of cells analyzed (n) for each case is indicated below the x-axis. These were obtained from 4 embryos from 3 independent experiments and each datapoint in the graph represents the average value for one embryo analyzed.