ZFIN Image: Keßler et al., 2015, Fig. 1

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Figure Caption

Fig. 1

Effects of the ste mutation on cardiac function. a, b Lateral view of wild-type (wt) (a) and ste^−/− mutant (b) embryos at 72 h post-fertilization (hpf). ste^−/− mutants (b) develop blood congestion at the cardiac inflow tract and a pericardial edema. c Heart rate at different time points in ste^−/− mutants (red) and wild-type littermates (blue). Bradycardia in ste^−/− mutants starts at 48 hpf and becomes more severe during further embryonic development. d Ventricular fractional shortening is unaffected in ste^−/− mutants compared to wild-type littermates at 72 hpf (53 ± 2.2 vs. 55 ± 3.1 %, n = 5, p = 0.7096), 96 hpf (58 ± 3.2 vs. 57 ± 1.9 %, n = 5, p = 0.7956) and 120 hpf (59 ± 1.9 vs. 61 ± 1.8 %, n = 5, p = 0.5586)

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Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Basic Res. Cardiol.