ZFIN Image: Almeida et al., 2016, Fig. 4

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Figure Caption

Fig. 4

Fewer oligodendrocytes mature in the posterior but not anterior spinal cord of kbp mutants.

A, Spinal cord of 96hpf Tg(mbp:EGFP) larvae with mature oligodendrocyte somas labelled. The myelin sheath of the very large diameter Mauthner axon (M), a reticulospinal axon, is visible in the ventral spinal cord except in the posterior region of mutants. Scale bar: 25 μm. B, The number of total, ventral and dorsal oligodendrocytes (OLs) is reduced in a 425μm long region of the posterior but not anterior spinal cord in mutants, compared to WTs. Data from N = 11 WT and N = 10 mutants (anterior) and N = 20 WT and N = 14 mutants (posterior). * indicates P<0.05; *** indicates P<0.001; see text for details. Error bars indicate ± SD.

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Acknowledgments

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