ZFIN Image: Zdebik et al., 2013, Fig. 1

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Figure Caption

Fig. 1

Invasive recordings using a patch pipette inserted into the optic tectum of 120 hpf old ZF larvae.

(A), 22 min recording of a buffer-injected control larva. Frequent spiking and also low level activity is present throughout the trace. (B), higher temporal and voltage resolution of the area marked in A. (C), kcnj10a morphant larva, showing genuine epileptic activity (marked with stars). Low-level activity is followed by a spontaneous large transient (arrowhead). Similar transients were seen while the fish showed brief total body contractions and could also be produced by a light tap on the recording setup (vertical arrow). The square marked “D” in C is shown in (D) at higher resolution.

Figure Data

Phenotype details

Acknowledgments

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