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Fig. S4
Prox1 expression in the nr5a2oz3 mutant liver and pancreas regions A) prox1 expression is reduced in the liver bud (red arrows) and absent in the pancreas bud (blue arrows) of nr5a2oz3/oz3 embryos at 72 hpf. B) prox1 expression is reduced in the liver bud (red arrows) and absent in the pancreas bud (blue arrows) of nr5a2oz3/oz3 embryos at 96 hpf, demonstrating that prox1 expression in the endoderm does not recover.
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Reprinted from Developmental Biology, 418(1), Nissim, S., Weeksb, O., Talbot, J.C., Hedgepeth, J.W., Wucherpfennig, J., Schatzman-Bone, S., Swinburne, I., Cortes, M., Alexa, K., Megason, S., North, T.E., Amacher, S.L., Goessling, W., Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development, 108-23, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.