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Fig. 4
Mutations in the genes freixenet (frx) and yquem (yqe) cause erythropoietic porphyria phenotypes. Mutant and wild-type embryos were examined under 330 to 380 nm UV light for autofluorescence. (A) A wild-type 2- day old embryo does not have autofluorescent blood. (B) The blood of 2-day old frxtu271 homozygotes is brightly autofluorescent under the same conditions. (C) The blood of 2-day old yqetp61 homozygotes is also autofluorescent. In addition, the yqetp61 mutants rapidly develop pericardial edema when exposed to bright light.
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