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Fig. 3
CREBBP-methylated species expression pattern at late blastula (30% epiboly) and during somitogenesis (6 ss). (A) Alignment of the epitopes of human CREBBP (hCREBBP) arginines R714 and R742 with the corresponding sequences of zebrafish crebbpa coding protein (CREBBPb or CBP-B). (B,C) Immunohistochemistry with CREBBP and CREBBPmethylated specific antibody as indicated at (B) 30% epiboly and (C) 6 ss. Nuclei are visualized in blue and a merged picture is shown. (B′, C′) Schematic illustration of subcellular localization of CREBBP and CREBBPmethylated proteins, with CREBBP labeled in red.
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