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Fig. 2
Ntla is essential during the gastrula stages. A-E: ntlacs/cs embryos were categorized as severe, moderate, or mild. Mild embryos had either a kinked tail (E) or an essentially normal body axis with minor tail fin defects at the most posterior end (D). F: Quantification of the results from placing embryos in the cold at the indicated stages. Severe and moderate phenotypes were grouped together since embryos were a continuum between the phenotypes shown in panels B and C. G-I: Close-up images showing the posterior tail fin defects observed in the mild embryos.
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