ZFIN Image: Hatzold et al., 2016, Fig. 10 S1

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Figure Caption

Fig. 10 S1

Morphology rescue of psoriasis mutant upon treatment with hydroxyurea and quantification of the non-alleviating effect of the treatment on NFκB activity in embryos as shown in Figure 10a,b.

(a-b) Live images of a 54 hpf psoriasis mutant treated with 50 mM hydroxyurea (HU) in E3 from 34 hpf onwards (b) and control mutant raised in E3 (a). Hydroxyurea does not rescue the pericardial edema (a,b), but blocks epidermal aggregate formation (a′,b′). (c) Mean fluorescence intensities of GFP in the posterior part of the tail fin were measured in maximum intensity projections of confocal images using the ImageJ software. n = 7-8. Error bars represent standard deviation.

Acknowledgments

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