Fig. S6
fgf8a is expressed in the anterior pro-sensory domain. (A) Whole-mount in situ hybridization, Probe: fgf8 anti-sense. fgf8 is expressed in the anterior prosensory domain at 36 hpf stage. jag1b+/+, jag1b+/-, and jag1b-/- embryos show similar fgf8a expression pattern. (B,C) Whole-mount in situ hybridization of pea3 (B) and erm (C) in WT embryos at 39 hpf stage. Probe: pea3 and erm anti-sense. pea3 and erm expression (arrowheads) is up-regulated in the middle region of the anterior prosensory domain. (D) TUNEL assay of DMSO and SU5402 treated embryos. (E) p-Erk3 immunostaining of DMSO and SU5402 treated embryos. Dorsolateral views with anterior to the left and dorsal up.