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Fig. 1
Vertebrate models used to study limb/appendage regeneration.(a) Phylogenetic relationship among three vertebrate taxa studied to determine conserved gene expression patterns in regenerating limb/appendages following blastema formation. These animal systems last shared a common ancestor ~420 million years ago. (b) Blastema tissues as shown by hematoxylin and eosin staining on paraffin tissue sections of regenerating zebrafish caudal fin, bichir pectoral fins and axolotl forelimbs. (* = blastema; dpa = days post-amputation).
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