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Fig. 4
Knockdown of hcfc1b results in reduced expression of the molecular markers associated with chondrocyte differentiation. (A and B) Ventral view of RNA in situ hybridization (ISH) of col2a1 or sox9a expression in non-injected (NI) control larvae or hcfc1b morphants (hcfc1b MO) at 3 days post fertilization (dpf). (C and Có) Ventral view of non-injected (NI) control, Tg(sox10:memRFP) larvae, or transgenic larvae injected with hcfc1b morpholino (hcfc1b MO) at 3 days post fertilization.
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Reprinted from Developmental Biology, 396(1), Quintana, A.M., Geiger, E.A., Achilly, N., Rosenblatt, D.S., Maclean, K.N., Stabler, S.P., Artinger, K.B., Appel, B., Shaikh, T.H., Hcfc1b, a zebrafish ortholog of HCFC1, regulates craniofacial development by modulating MMACHC expression, 94-106, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.