ZFIN Image: Quintana et al., 2014, Fig. 3

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Figure Caption

Fig. 3

NCCs are specified and migrate correctly in morphant animals. (A and B) Dorsal view (anterior to posterior from left to right) of Tg(Sox10:mRFP) embryos injected with an hcfc1b targeting morpholino (hcfc1b-MO) were visualized for RFP expression at the 12 somite stage. (C and D) Sagittal view of non-injected (NI) or hcfc1b MO injected Tg(Sox10:mRFP) larvae at 30 h post fertilization (hpf). Arrows depict the formation of the pharyngeal arches in both wildtype and morphant animals. (E-H) In situ hybridization (ISH) of dlx2a in non-injected (NI) and hcfc1b morphants (hcfc1b MO) at 1 day post fertilization (dpf). (I and J) Lateral view of non-injected Tg(prdm1a:EGFP) (NI) or Tg(prdm1a:EGFP) embryos injected with the hcfc1b targeting morpholino (hcfc1b MO). The encircled area depicts posterior arch expression of EGFP in transgenic animals.

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Expression / Labeling details

Acknowledgments

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Reprinted from Developmental Biology, 396(1), Quintana, A.M., Geiger, E.A., Achilly, N., Rosenblatt, D.S., Maclean, K.N., Stabler, S.P., Artinger, K.B., Appel, B., Shaikh, T.H., Hcfc1b, a zebrafish ortholog of HCFC1, regulates craniofacial development by modulating MMACHC expression, 94-106, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.