ZFIN Image: McCarthy et al., 2016, Fig. S3

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Figure Caption

Fig. S3

The postchordal neurocranium is not lost in dlx3b;foxi1 knockdown embryos. (A-B) DIC images of 24 hpf embryos and (A′-B′) the same embryo at 5 dpf wholemounted neurocrania with viscerocrania removed. Anterior is to the left. (A-A′) Un-injected control embryos show an otic placode at 24 hpf (arrowhead) and normal posterior neurocranium at 5 dpf. (B-B′) dlx3b;foxi1 double morpholino-injected embryos lack an otic placode at 24 hpf, but retain most of the posterior neurocranium at 5 dpf (arrowheads point to missing anterior basicapsular commissure). (C) Additional examples of dlx3b;foxi1 double morpholino-injected embryos at 5 dpf (arrowheads point to missing anterior basicapsular commissure). abc- anterior basicapsular commissure, scale bar= 20 µm.

Acknowledgments

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Reprinted from Developmental Biology, 415(2), McCarthy, N., Sidik, A., Bertrand, J.Y., Eberhart, J.K., An Fgf-Shh signaling hierarchy regulates early specification of the zebrafish skull, 261-77, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.