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Fig. 7
Gβ1 acts synergistically with Cxcr4b to regulate migration of the pLLP. (A-D) Epifluorescence images of the following 48-hpf Tg(-8.0cldnb:lynEGFP) embryos: WT uninjected control (A), cxcr4b(+/-) (B), WT injected with a low dose of gnb1a/b MO1 (1 ng, C) and cxcr4b(+/-) injected with a low dose of gnb1a/b MO1 (1 ng, D). Lateral views with anterior to the left; white arrowheads, NMs; and red arrows, posterior-most deposited NM. (F) Quantification of pLLP migration in embryos, as indicated in Fig. 2.
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Reprinted from Developmental Biology, 385(2), Xu, H., Ye, D., Behra, M., Burgess, S., Chen, S., and Lin, F., Gbeta1 controls collective cell migration by regulating the protrusive activity of leader cells in the posterior lateral line primordium, 316-27, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.