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Fig. 2
Gβ1, but not Gβ4, is required for migration of the pLLP. (A-E) Epifluorescence images of 48-hpf Tg(-8.0cldnb:lynEGFP) control embryos (A), embryos injected with MOs targeting gnb1a (B, C), gnb1a/b (D) or gnb4a/b (E). All images are lateral views with anterior to the left. White arrowheads, NMs. The embryo was subdivided into six equal sections (zones 1-6) from the ear to the tip of the tail. (F) Quantification of pLLP migration relative to the position of the posterior-most deposited NM (red arrows in A-E). The number of animals/injection is indicated.
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Reprinted from Developmental Biology, 385(2), Xu, H., Ye, D., Behra, M., Burgess, S., Chen, S., and Lin, F., Gbeta1 controls collective cell migration by regulating the protrusive activity of leader cells in the posterior lateral line primordium, 316-27, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.