ZFIN Image: Suli et al., 2016, Fig. S1

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Figure Caption

Fig. S1

Afferents persist after HC death. Afferent innervation of OP1 anterior lateral line neuromasts; in the anterior lateral line of a 5dpf Tg(neuroD:EGFP) transgenic larva was imaged with a Zeiss spinning disc microscope once every 5 min for a total of 13 hours. After the first image (A) was taken, 400µM neomycin was added to the preparation to kill the HCs (B-D). Following 1 hour of treatment, neomycin was washed out and the afferent innervation was imaged again once every 5 minutes for 12 hours (E-K). Even though HCs die from neomycin treatment (Harris et al., 2003, Ma et al., 2008), afferents still persist and do not significantly retract. At this magnification it is unclear if afferent endings stay within the neuromast or just remain next to it.

Acknowledgments

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