|
Fig. 6
Neural plate and mesoderm remain coupled in Has2 deficient embryos. A: Frame 1 from a time-lapse sequence of a has2 deficient embryo. A neural plate (np) nucleus is marked with a yellow dot, a mesodermal (mes) nucleus with a red dot, and enveloping layer (evl) nucleus with blue dot. Arrow indicates tissue movements. Midline of neural plate marked with an arrowhead. Orientation and position as for Figure 5E. B: Frames 1 to 10 of time-lapse superimposed to reveal parallel tracks of neural and mesodermal nuclei. C: Trajectories of neural plate (yellow) and mesoderm (red) nuclei on Has2 depleted embryo. D-F: Analyses in cell directionality (D), persistence (E), and angular speed (F), reveals movements of neural plate and mesoderm cells remain coupled in Has2 depleted embryos.