Image
|
Figure Caption
Fig. 3
id4 mutant larvae exhibit retrograde blood flow after heat stress conditions. Embryos from an incross of id4 heterozygous animals were exposed to heat stress at 48 hpf for 1 h at 37 ºC, followed by bright field spinning disk microscopy. (A, B) Single frames (at end of ventricular systole) from blood flow movies of id4+/+ and id4-/- siblings respectively. (C) Quantification of embryos showing retrograde flow. Scale bars, 20 µm. A, Atrium; AVC, Atrioventricular Canal; V, Ventricle. Blood flow movies of id4+/+ (id4 wt video 1) and id4-/- (id4 mut video 2) are available in supplementary information.
Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Biology, 412(1), Ahuja, S., Dogra, D., Stainier, D.Y., Reischauer, S., Id4 functions downstream of Bmp signaling to restrict TCF function in endocardial cells during atrioventricular valve development, 71-82, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.