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Fig. S6
Changes in Src activation and localization upon expression of mouse and zebrafish PrPs in MCF-7 cells. A. WB analysis with lysates of MCF-7 cells expressing EGFP-tagged PrPs. B. Subcellular distribution of EGFP-PrPs and Src immunofluorescence in MCF-7 cells. Scale bar = 10 µM. C. Quantification of Src immunofluorescence at cell-cell contact sites. Graph depicts percentages of cells (average values ± SEM) with different percentage of Src at cell-cell contact sites. Values were normalized to whole cell Src immunofluorescence.
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