ZFIN Image: Sisson et al., 2015, Fig. 3

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Figure Caption

Fig. 3

Cranial neural crest cell migration and specification is unaffected in gpc4 and wnt5b mutants. (A–O) Neural crest specification appears normal within gpc4 and wnt5b mutants Scale bar = 100 µm. (A–I) Pre-migratory neural crest markers. 6 somites. (J–O)Pharyngeal arch markers. (J–L) 28 hpf. (M–O) 32 hpf. (P–R) Migration of neural crest appears to be unaffected in gpc4 and wnt5b mutants when compared to wild type fish. Tg(fli1a:EGFP)^y1 embryos have neural crest derived cells labeled by GFP expression. Embryos were fixed at 33 hpf and stained with the Alcama (Zn5) antibody (red). Pharyngeal arches are numbered. Scale bar = 50 µm.

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Acknowledgments

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Reprinted from Mechanisms of Development, 138 Pt 3, Sisson, B.E., Dale, R.M., Mui, S.R., Topczewska, J.M., Topczewski, J., A role of glypican4 and wnt5b in chondrocyte stacking underlying craniofacial cartilage morphogenesis, 279-90, Copyright (2015) with permission from Elsevier. Full text @ Mech. Dev.