ZFIN Image: Cortés-Campos et al., 2015, Fig. 4

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Figure Caption

Fig. 4

Hypothalamic progenitors generate glial and neuronal cells. (A-F) Neurospheres differentiated after 7days in vitro. (A-C) Differentiated cells surround the core of cells positive for nestin (arrow head) and extend cellular projections that are reactive to GFAP (arrows). (D-F) The reduced number of Sox2 positive cells (arrows) and the high number of cell processes reactive to Vimentin (arrow heads) suggests that progenitors have differentiated into glial cells. (G-L) Neurospheres reactive to GFAP show (G-I) a reduced number of cells positive for PCNA (arrows), (J-L) high number of neurons (arrows) and differentiated glial cells (arrow heads). Scale bar 25µm, n=3 plates derived from different cell cultures.

Acknowledgments

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