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Fig. 3
Zimp7 overexpression produces axial mesoderm defects. Injection of 10–800 pg of zimp7 mRNA produced malformations that were classified into four categories. (A) Type1 embryos are very severely defective. Type 2 embryos showed cyclopia, anterior truncations, bent tail and shortened body. Type 3 embryos presented a shortened body axis. Lateral views. (B) Distribution of embryonic malformations. Total numbers of embryos are shown at the top. Defects induced by zimp7 mRNA are dose dependent.
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Reprinted from Developmental Biology, 403(1), Moreno-Ayala, R., Schnabel, D., Salas-Vidal, E., Lomelí, H., PIAS-like protein Zimp7 is required for the restriction of the Zebrafish organizer and mesoderm development, 89-100, Copyright (2015) with permission from Elsevier. Full text @ Dev. Biol.