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Fig. 4 NOTCH ChIP-seq in ANGPTL2-stimulated CD34+ cells.
(A) Enriched transcription factor motifs at the peaks of NOTCH binding sites from NOTCH ChIP-seq. Parentheses indicate E values for the significance of the motif. An embedded RBPjK ((consensus motif (red box) was found within the ZNF143 motif as previously described (Wang et al., 2011). (B) Examples of MYC-related categories from GREAT analysis of NOTCH ChIP-seq. (C) IPA network analysis of NOTCH ChIP-seq bound genes revealed a dense network of target genes centered on MYC.
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