Image
|
Figure Caption
Fig. 6
gata1 is required to initiate mpx expression in the ICM region, but later represses it. (A–H) pu.1 expression is greatly increased (n=16/16 and 31/31) while mpx expression is greatly reduced (n=66/66 and 26/26) as analyzed by ISH in gata1 MO knockdown embryos at the 20-somite (A–D) and 24-somite (E–H) stages, respectively. (I–P) Both pu.1 and mpx expression are greatly increased in gata1 morphant embryos at 26 hpf and 32 hpf (n=35/35 and 30/33 for pu.1 expression; n=27/31 and 21/24 for mpx expression at 26 hpf and 32 hpf, respectively). Dorsal is up and anterior is to the left in all panels.
Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Biology, 393(1), Glenn, N.O., Schumacher, J.A., Kim, H.J., Zhao, E.J., Skerniskyte, J., Sumanas, S., Distinct regulation of the anterior and posterior myeloperoxidase expression by Etv2 and Gata1 during primitive Granulopoiesis in zebrafish, 149-59, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.