Fig. 3
foxc1a is required for fin-innervating motor nerves to convert at the plexus. (A) Lateral (composite) view of a 96-hpf-old Tg(mnx1:GFP) larvae expressing GFP in all motor nerves. Yellow dashed boxes mark anterior segments (AS) and posterior segments (PS) considered in this study; white dotted area outlines the pectoral fin. (B,C) Compared with wild-type larvae, trunk innervation (posterior segments) is unaffected in foxc1a mutants. (D-G) By contrast, three out of the four fin-innervating nerves in foxc1a mutants display axonal defects at 48hpf (D-G) and at 96hpf (H-K). Dotted areas outline the pectoral fin, arrowheads indicate the position of the fin plexus and arrows indicate the fourth pectoral fin nerve. Cyan asterisks indicate ectopic fasciculation; red asterisks mark defasciculation. Scale bars: 50µm.